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Application examples

Rompun: A tried and trusted anaesthetic technique, simple and reliable.

In clinical horse practice Rompun is used for sedation and analgesia alone or in combination with other drugs, and for premedication prior to general anaesthesia.

Rompun alone can be used for:

  • Sedation


Sedation with Rompun enables the practitioner to carry out diagnostic and therapeutic procedures, as well as minor surgery such as:

  • radiography
  • endoscopy
  • dental work
  • surgical wound treatment
  • hoof treatment

Rompun sedation in combination with local anaesthesia extends the spectrum of possible therapeutic interventions. Three to five minutes after IV injection an effective deep sedation is achieved, lasting for about 20 to 30 minutes.The horse remains standing with lowered head and a wide based stance, and can be handled easily.

Higher doses do not increase the depth of sedation but prolong the effect.
Sedation at the recommended doses is profound and, apart from slight sensitivity to noise, the horse is indifferent to its surroundings. Despite looking deeply sedated, the horse may kick in response to only superficial stimuli; therefore normal handling precautions are essential.
Rompun is most effective in horses when given intravenously. Intramuscular application requires 2 - 3 times the intravenous dose with the sedative effect only beginning 10 -15 minutes after the injection.
Before carrying out surgery on the standing horse or administering an anaesthetic to achieve recumbency, it is important to monitor the horse’s reaction to premedication with Rompun which usually occurs in the order shown in the table.

Rompun Dosage for Sedation of Horses, Sequence of signs occurring after IV injection with Rompun

Rompun: The combination with other sedatives and analgesics.


The horse should be kept in quiet surroundings and, if possible, should not be moved to another place to perform diagnostic or treatment procedure. Immediately after injection of Rompun, the horse should be left undisturbed for at least five minutes to achieve the best possible sedative effect .

  • Analgesia

The analgetic effect of Rompun is very important for the veterinarian in daily practice. Rompun is used to carry out painful diagnostic and therapeutic procedures, but, because of its analgetic effect on the viscera, it is also a valuable tool in the management of colic in horses.
Under Rompun sedation, analgesia is usually present in the body and the viscera, but is less marked in the legs, so that additional local anaesthesia or combination with opioids may be necessary.

  • Anaesthesia of a horse with Rompun, Ketamine and Guaifenesin is shown left.

Rompun in combination:

To increase the depth of sedation, Rompun is widely used in combination with other sedatives and analgetics for minor surgery such as skin suture, excision of small cutaneous tumors, or standing castration under local anaesthesia.


Neuroleptanalgesia Rompun and Fentanyl*
0.4 mg/kg BW Rompun IV after 3 to 10 minutes up to 1 µg/kg BW Fentanyl IV


*Fentanyl Janssen


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